Shimadzu

ICPMS-2030 | Inductively Coupled Plasma Mass Spectrometer

With its newly developed collision cell and optimized internal structure, the Shimadzu ICPMS-2030 provides superior sensitivity. At the same time, thanks to the adoption of its proprietary mini-torch unit and provision of an Eco mode, the quantity of argon gas needed for analyses has been greatly reduced to the industry’s lowest levels. As a result, low running costs are assured. The Development Assistant function of the software automatically sets the optimal analysis conditions for quantitative analysis. Then, after measurements are complete, the Diagnosis Assistant function automatically checks the validity of the necessary data. While reducing the burden on the user, the efficiency of analyses is enhanced and the reliability of the data can be increased. It complies with FDA 21 CFR Part 11.

ICPMS-2030 overview

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Nexis GC-2030 | Gas Chromatograph

In today’s environment, results are needed regardless of whether the analyst is working in the laboratory, the office, or from home. With the flexibility to accommodate a variety of applications, the Shimadzu Nexis™ GC-2030 supports the analyst’s procedures beyond the laboratory, at virtually any location.

Nexis™ GC-2030 overview

• Delivers the Best Performance Regardless of Location: Laboratories today require faster and higher performance analysis. The Nexis GC-2030 features Analytical Intelligence to help achieve these goals. Clean Pilot, a system conformity test, and LabSolutions™ can provide an automated workflow together with remote operation and monitoring from instrument startup to analysis completion. Automated workflows incorporate the work-style habits of experienced analysts. The result is reliable data collected over extended periods and higher productivity.
• Information at Your Fingertips: Analysts will benefit from the touch panel interface, which features clear graphics that display information instantly whenever needed. The user-friendly interface leaves the operator free to focus on obtaining optimal analytical results.
• Tool-free Column Installation: ClickTek™ connectors* make tool-free column installation a snap. The click sensation felt when finished attaching the column provides a more reliable connection and ensures a better seal under all operating conditions. In addition, a light has been installed inside the oven to brightly illuminate the area at hand, easing the burden on the operator when attaching columns.
• One-Touch Inlet Maintenance: The injection port can be opened or closed without tools by simply sliding the ClickTek lever. Replace the insert, slide the lever and feel the click for a leak-free install every time.
• Clean Pilot Function: During typical GC startup and batch analyses, in order to dispose of impurities remaining within the column, the operator has to implement conditioning by manually raising the oven temperature. Using the Clean Pilot function, conditioning is performed automatically, leading to more stable analytical results while easing the burden of lab work.
• LabSolutions Direct Accommodates Remote Work: LabSolutions Direct is a remote access tool used to control or monitor GC systems via a simple user interface on a commercially available smartphone or tablet. Consequently, analyses can be performed while monitoring the status of instruments from locations away from the laboratory.

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GC-2014 | Gas Chromatograph for Versatile Applications

User-friendly with high cost-performance, the Shimadzu GC-2014 gas chromatograph is an excellent option for routine analysis. It offers great flexibility with support for both packed columns and capillary columns, and includes a self-diagnostics function to prevent downtime and maximize lab efficiency.

GC-2014 Gas Chromatograph overview

Easier to understand, simpler operation

A large LCD displays chromatograms and method parameters. Graphical popup screen that clearly guides operation so that operation errors are prevented. The built-in Help function almost eliminates need for familiarization training.

Self-diagnostics validate that the instrument before injection. Regular diagnosis prevents unexpected downtime.

Expandability to Support all Types of Analysis

Select from four types of injection units and five types of detectors according to the target compounds and analysis objective. Modular injection units, detectors and auto-injectors can be easily added after installing the unit in your lab. Three Injection Units and Four Detectors can be simultaneously installed.

Effective use of valuable column resources is maintained by using the 40-mm pitch glass column the same as Shimadzu GC-7, 9, 12, 14, 15 and 16 Series.

Performance lifted to a higher level

The GC-2014 Series is equipped with the advanced flow controller (AFC) technology. This digital control is standard for not only capillary columns, but packed columns as well. Accurate flow rate control via AFC has higher-level repeatability of retention time and peak area, enabling a higher level of analyses.

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HS-20 NX Series | Headspace Sampler

The Shimadzu HS-20 Headspace Sampler developed as the best solution for volatile component analysis, has been improved and introduced as the NX series. The excellent basic performance and user-friendly design provide a powerful solution for scientists in both research and quality control laboratories.

HS-20 NX Series Headspace Sampler overview

• Ultra-low carryover: The HS-20 NX series uses the isolation gas flow to reduce carryover to 1/10 of conventional models. It supports a wide range of chemical species, including high-boiling point compounds and high-polar compounds, and provides reliable analytical results.
• The Isolation Gas Flow: The isolation gas flow prevents sample diffusion from the vent channel, which has been a problem with conventional headspace samplers. (patent pending) Carryover of highly adsorptive compounds is reduced, eliminating the need for
  repeating blank runs.
• Residual Solvents Analysis in Pharmaceuticals USP <467>: In the residual solvents analysis of medicines, analysis with an aqueous solvent may be performed after analysis with a DMF solvent, but with the HS-20 NX, carryover of DMF is not a problem. HS-20 NX is effective for the analysis of samples with different type of solvents or large concentration differences.
• Excellent reproducibility: High analysis reproducibility is achieved by the sample vial loading from the lower part of the oven. Shimadzu’s unique sample vial delivery system minimizes heat dissipation in the HS oven as the vial enters and leaves the oven, and maintains high temperature stability during repeated analyses.
• High-temperature capability and short inert flow path: The vial oven and sample line can be set to 300 °C and the transfer line can be set to 350 °C. In addition, the sample path is designed to be inert and at the shortest distance, so that adsorption of analytes, including high-boiling compounds, and peak broadening are suppressed.
• Ready to use an alternative carrier gas: The HS-20 NX series with the latest electronic AFC (Advanced Flow Controller) offers highly accurate carrier gas control at constant linear velocity, constant flow, and constant pressure modes. It supports the use of nitrogen and hydrogen as alternative carrier gases and makes it easy to transfer analysis methods.

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i-Series Plus | High Performance Liquid Chromatograph

Amid increasing calls for improved work efficiency and a more flexible working style, ideas of LC analysis are changing. The time has come for an HPLC that delivers rugged, reliable results with less frequent interaction by the analyst. The new, integrated Shimadzu i-Series LC system maintains the excellent performance of its predecessor while addressing the need for automation efficiency.

i-Series Plus features

• Innovative: Remote instrument operation and monitoring allow analyses to be performed remotely, thereby reducing the time spent in the laboratory.
• Intelligent: Software integration ensures both data reliability and improved work efficiency.
• Intuitive: Intuitive operation ensures an efficient workflow.

i-Series Plus lineup

• HPLC model : LC-2050 series (pressure resistance 50 MPa): Three types of detector setup (UV, PDA, detector-less) are available to suit your analysis methods and aims. In addition, we provide models both with oven cooling functions (C model) and without.
• UHPLC model : LC-2060 series (pressure resistance 70 MPa): This is our 70 MPa UHPLC model. The method transfer system provides excellent support for running UHPLC and HPLC methods on one device.

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GCMS-TQ8050 NX | Triple Quadrupole GC-MS

The Shimadzu triple-quad GCMS-TQ8050 NX is capable of performing unprecedented quantitative GC-MS/MS analyses of ultra-trace amounts, down to the femtogram level. Equipped with a new, highly efficient detector and three forms of noise-reduction technologies, the GCMS-TQ8050 NX has never been more important in industries such as food safety, cannabis testing, forensics, and more.

GCMS-TQ8050 NX Triple Quadrupole GC-MS overview

Enhanced sensitivity enables ultra-trace level analysis

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GCMS-TQ8040 NX | Triple Quadrupole GC-MS

The Shimadzu triple-quad GCMS-TQ8040 NX features smart technologies to boost the efficiency of routine analytical work. For example, Smart MRM provides fully-automated MRM method development. It automatically determines all optimum transitions and collision energies, seamlessly incorporating them into the Smart Database Series. With features like this, the GCMS-TQ8040 NX GC-MS/MS is so smart it almost runs itself! Perfect for applications in fields such as environmental monitoring and food science.

GCMS-TQ8040 NX overview

Simplified user maintenance allows operators to change parts quickly

• Active-Time Management™ That Accurately Determines Operation Time: The mass spectrometer has to be operated in a vacuum condition, the startup and stopping of the system takes time depending on the condition. Determining this can be a challenge. Since the amount of time that the system takes when starting up or stopping is displayed in real time, it is easy to accurately determine when maintenance of the ion source or analysis is possible. Moreover, tasks that until now needed to be performed by the user, such as leak checks upon system startup and auto tuning, are now performed automatically.
• Time Management during Injection Port Maintenance: The Easy sTop function, used to safely maintain the sample injection port without releasing the vacuum, displays the remaining time (coolingdown time) when the septum or the insert can be replaced in real time. Maintenance time can be minimized by understanding the accurate remaining time. Furthermore, by using a ClickTek nut on the top of the sample injection port, the port can be opened or closed without tools, by simply using fingers to twist a lever. That enables faster and easier insert replacement than ever before.
• Time Management for Continuous Analysis: By displaying the time required for continuous analysis in real time, the time when the current continuous analysis will finish can be accurately confirmed. This increases the instrument operating time (active time) by reducing standby time required during continuous analysis or while switching between different users. In addition, because this function makes it easier to schedule the timing for analysis preparations, such as sample preparation and pretreatment, based on the finish time of the previous analysis, it enables analytical processes to be performed more efficiently, which can help improve work-life balance.

Smart Database Series provides automated method development

• Smart Database: The Shimadzu “Smart Database” is a database file for creating the method files using “Smart MRM” function. In addition to compound information and transitions, retention index can be registered in the database file. Method creation can be proceeded without calculating the retention time by analyzing the standard samples when using the Automatic Adjustment Retention Time (AART) function. In addition to MRM information, Scan and SIM ion information, mass spectra and calibration curve information from the internal standard method can also be registered in the database file. This allows users to create their own database easily.

Smart MRM sets method to maximize sensitivity

• Smart MRM: Smart MRM makes method development quick and easy. Whether starting from scratch to optimize transitions and collision energies for new compounds, or starting from an MRM database of known target analytes to build a custom MRM method, Smart MRM takes the stress and difficulty out of method development.

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Nexera lite inert | High Performance Liquid Chromatograph

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GCMS-QP2020 NX | Single Quadrupole GC-MS

The Shimadzu single quadrupole GCMS-QP2020 NX gas chromatograph-mass spectrometer (GC-MS) not only boasts the best performance in its class, but also the highest efficiency. This new high-end single-quad GCMS excels in both ease-of-use and robustness. The role of high-performance analytical instruments is expanding in areas as diverse as environmental pollution monitoring, forensics and material science. Whatever your field, the efficient and reliable GCMS-QP2020 NX is tailored to meet the needs of your laboratory.

GCMS-QP2020 NX overview

Smart Performance

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LCMS-9030 | Quadrupole Time-of-Flight LC-MS

The Shimadzu LCMS-9030 quadrupole time-of-flight (Q-TOF) mass spectrometer is a powerful instrument that integrates the world’s fastest and most sensitive quadrupole technology with TOF capabilities for accurate mass measurement.

The LCMS-9030 provides superior sensitivity for quantitative and qualitative analysis of samples over a wide concentration rane, including ultra-trace compounds. Patented technologies ensure high resolution and excellent mass measurement accuracy (MMA), supporting structure elucidation and identification of unknown compounds. High throughput is achieved with Shimadzu’s unique acceleration technologies designed for high-speed data acquisition.

LCMS-9030 features

High-Efficiency Quadrupole Technologies

• UFaccumulation™ (Pat. US 10020181): Ion accumulation in the collision cell, synchronized perfectly with short cycles of data acquisition, maximizes sensitivity.
• UFgrating™ (Pat. US 9048082): Shimadzu’s world-class manufacturing capability has enabled the ion acceleration electrode to be made with substantial mechanical strength. This grating is able to withstand the high voltages needed for ultrafast ion pulsing.
• UF-FlightTube™ (Patent Pending): Mass accuracy needs mass stability. Shimadzu’s temperature-controlled UF-FlightTube requires less frequent calibration, enabling you to run more samples.
• iRefTOF™ (Pat. US 8772708, 9490114): A computationally ideal electrostatic field has become a reality. Meticulously manufactured plate electrodes are stacked to create a reflectron which turns ions with no compromise in resolution or sensitivity.

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LCMS-8045 | Triple Quadrupole LC-MS

Equipped with a heated ESI probe, the Shimadzu LCMS-8045 has the highest sensitivity in its class. The heated ESI probe, high-temperature heating block, desolvation line (DL) and drying gas, all act to promote desolvation and prevent contamination due to the penetration of liquid droplets into the MS unit. This improves the robustness, so reliable and high-accuracy data can be obtained over the long term. The LCMS-8045 also achieves the world’s fastest scan speed (30,000 u/sec) and polarity switching speed (5 msec). These enable ultra-high-speed, high-sensitivity analysis. The excellent cost performance of this system is demonstrated in food safety, environmental analysis, and other quantitative analyses, it can be upgraded to the LCMS-8060.

LCMS-8045 features

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LCMS-2020 | Ultra Fast Liquid Chromatograph

The Shimadzu LCMS-2020 is optimized for the Prominence UFLC/UFLCXR Ultra Fast Liquid Chromatograph. Novel patent-pending technologies offer significantly enhanced scan speed and positive-negative ion polarity switching time, which are essential for UFLC, and simultaneously boost sensitivity. The instrument combines the excellent compound selectivity that is a feature of the mass spectrometer with significantly enhanced total productivity – from method development to analysis. The LCMS-2020 plays a useful role in a range of fields, including the synthesis of compounds in the pharmaceutical and chemical industries.

LCMS-2020 features

• UF Switching: To detect both positive and negative ions, analysis is performed while switching between the positive and negative ionization modes. The LCMS-2020 adopts patented high-voltage power supply technology (Patent: US7855355) to achieve an ultra-fast polarity switching time of just 15 msec.
• UF sensitivity: Superior sensitivity, repeatability, and linearity are achieved, thanks to the newly developed Qarray® optics.
• UFscanning: In MS scanning, a range of mass to charge ratios are determined in successive 0.1 m/z steps. This is controlled by applying a rapidly changing voltage to the quadrupole (quadrupole rods). By adopting Shimadzu’s proprietary scanning technology (Patent: US8188426), high ion transmission is achieved without sacrificing sensitivity or resolution, even during high-speed scans up to 15,000 u/sec. Very narrow UFLC peaks can now be properly detected in scan mode acquisition.

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AXIMA Assurance | MALDI Floor Standing Instrument

The Shimadzu AXIMA Assurance a Linear MALDI-TOF mass spectrometry for reliable mass information, an affordable, robust option for all laboratories requiring routine manual or automated analysis of a wide variety of sample classes.

AXIMA Assurance overview

• Linear MALDI-TOF mass spectrometry for reliable mass information.
• An affordable, robust option for all laboratories requiring routine manual or automated analysis of a wide variety of sample classes.
• High sensitivity system using a variable repetition rate 50 Hz N2 laser and a variety of target formats to meet all sample throughput requirements.

AXIMA Assurance features

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LabSolutions CS | Laboratory Software

LabSolutions CS, from our partner Shimadzu, features an innovative operating environment and provides complete data management to ensure secure information in networked laboratories.

LCs and GCs are used extensively in quality control and research and development departments in a wide range of industries, including pharmaceutical, chemical, and food. Recently, an increasing demand for food safety and environmental analysis and measurement has led to a dramatic increase in the number of samples being analyzed which, in turn, has resulted in demands for faster, easier-to-use instruments and software. In the pharmaceutical industry, compliance to regulations and guidelines, such as CSV and PIC/S GMP, U.S. FDA 21 CFR Part 11, Data Integrity and so on, and the proper, efficient management of instruments and analytical data are required. With this background, faster, more efficient management of instruments and data is essential. LabSolutions is a network-compatible analysis data system capable of meeting these needs.

Features of LabSolutions CS

• Comfortable Operating Environment: One Software, Operating Status of Equipment, Remote Access
• Safe and secure data management: database management, solid security
• Total support for regulatory compliance: CSV (IQOQ Validation) Support, Configuration Management of Client PC, Documentation Support
• Multi-data report:Reduced Validation Workload, Report Creation for Various Instruments, Various Report Templates
• Peak integration algorithm: Highly Accurate Detection of Shoulder Peaks, Simple Adjustment of Peak-baseline Processing
• Report set: Visualization of the Sequence of Analysis Operations, Sequence of Analysis Protected Automatically, Digitization of the Confirmation Process

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LabSolutions DB | Laboratory Software

LabSolutions DB, Laboratory Software from our partner Shimadzu, integrates a data management function with LabSolutions LC/GC and is compliant with the ER/ES Regulations. It is optimally configured for customers using a PC and delivers secure data management with a PC.

It is recommended for the following customers

• Facilities with only a few instruments (maximum of 4 units/PCs)
• Facilities where network connections are not required
• Facilities interested in ER/ES compliance and limited to stand-alone systems

Features of LabSolutions DB Laboratory Software 

Safe and secure data management

• Database management prevents mistakes
• Solid security
• Control and analysis are possible from PCs other than the analysis PC
• Improved managerial efficiency with system information integrated with the server

Total support for regulatory compliance

• Support functionality for CSV (IQOQ Validation)
• Configuration management of client PC LabSolutions software not required
• Support for document creation

Multi-data report

• Features simplified preparation of free formats and a reduced validation workload using change control
• Enabling report creation for various instruments
• Report templates for various standard tests provided as standard

Peak integration algorithm

• i-PeakFinder, a new peak integration algorithm for LabSolutions, is a completely automated integration function that can detect peaks with high levels of accuracy without requiring special parameter adjustments.

Column manager

• Analytical column management tool
• Easy confirmation of usage and frequency in use of column
• Easy confirmation of the analysis result using the column
• Audit trail of column management
• Easy management of column information
• Confirmation of usage in use of column
• Analysis history of column

Report set

• Strong support for ensuring the reliability of analysis data and enhancing productivity
• Provided report set function enables visualization of computer operations and improves procedural efficiency

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iMScope QT | Imaging Mass Microscope

Inheriting the concept of a mass spectrometer equipped with an optical microscope from the iMScope series, the iMScope QT Imaging Mass Microscope is also Shimadzu‘s flagship model for MS imaging with a Q-TOF MS(LCMS-9030).

The iMScope QT boasts not only fusion with morphology studies but also excellent speed, sensitivity, and spatial resolution, clearing the way to next-generation mass spectrometry imaging.

iMScope QT Imaging Mass Microscope overview

Combined Analysis

• Fusion of observations from an optical microscope with MS images (exclusive to Shimadzu)
• MS images can be obtained flexibly and matched to observation images, either the entire image area or detailed portions of it.

Quantification and Distribution

• Obtain qualitative and quantitative information from LC-MS as well as position information from mass spectrometry imaging (MSI) with a single instrument.
• The combined system, which can perform LC-MS analysis in addition to MSI analysis, provides both distribution information and quantitative analysis.

High Resolution, Speed and Accuracy

• Acquisition of accurate, high-speed, high-resolution MS images, together with efficient data analysis
• Combination of the high-accuracy, high-speed LCMS-9030* with high-resolution mass spectrometry imaging

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Nexera LC-40 Liquid Chromatography System

The Shimadzu Nexera LC-40 Liquid Chromatography system has a modular set-up that offers full flexibility, to support even the most challenging applications. The low system volume and detectors with world-leading sensitivity enable excellent performance for method development, routine analysis, as well as for high-throughput requirements. Built-in Analytical Intelligence features ensure maximum reliability and ease-of-use. The Nexera series makes lab management simple by integrating IoT and device networking, enabling users to easily review instrument status, optimise resource allocation, and achieve higher throughput.

Features of the Nexera LC-40 Liquid Chromatography System

• Absorbance Detector SPD-40 / SPD-40V and Photodiode Array Detector SPD-M40
  • Temperature control improves performance stability.
  • Analytical data is linked to information about consumables to ensure traceability.
• Solvent Delivery Unit LC-40 Series
  • Auto-diagnostics to detect problems during analysis, and an auto-recovery function.
  • Reduces space requirements with a dual solvent delivery system.
• Autosampler SIL-40 Series / PLATE CHANGER
  • The injection speed is twice as fast as previous models, shortening multi-analyte processing times.
  • Can perform continuous analysis on up to 44 microtiter plates.
  • High reproducibility and ultra-low carryover for micro-volume injections.
  • Automated sample preparation functions such as diluting samples, adding internal standards, and performing derivatization reactions, reduce labor.
• Mobile Phase Monitor MPM-40
  • Reservoir tray weight sensors monitor the remaining mobile phase in real time.
• System Controller SCL-40, CBM-40
  • Supports remote monitoring via a smart device.
  • Mobile phases can be purged and baselines checked easily via the touch panel.
• Column Oven CTO-40 Series
  • Injection count, analysis pressure, and other column information is automatically managed.
  • Easy column attach/detach mechanism prevents peak broadening.
  • LabSolutions monitors column degradation level based on usage history.

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LCMS-2050 | Single Quadrupole LC-MS

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GC-2010 Pro | Gas Chromatograph

The Shimadzu GC-2010 Pro represents a new generation in Routine GC. Fast oven heating and cooling reduces the analysis time and allow high sample throughput. Based on high-end GC technology, it combines easy operation with efficient analysis and excellence in sensitivity and precision.

GC-2010 Pro Gas Chromatograph overview

• Flexible lineup for various analysis: Two analytical lines can be operated simultaneously for different applications
  • Achieving excellent reproducibility
  • High-speed analysis
  • Rapid oven heating / cooling
  • Constant linear velocity mode quickly determines separation conditions
  • Gas saver function reduces helium consumption
• Achieving excellent reproducibility: All units including the column oven, flow controller and sample injection unit are comprehensively optimized at the design stage to achieve world-class repeatability of peak area and peak height. The large vaporization capacity ensures excellent repeatability, even when using solvents that are highly volatile upon injection, such as acetone. Long-term stability of retention time is realized by the new room compensation technology built into the advanced flow controller (AFC).
• High-speed analysis: High-speed analysis with narrow bore capillary columns reduces analysis time and improves sample throughput. GC-2010 Pro has excellent flow and pressure control system, which can meet the requirements of rapid analysis with conventional configuration and effectively improve the analysis efficiency.
• Rapid oven heating / cooling: GC-2010 Pro incorporates a double-jet cooling system, which enables the reduction of cooling time from 450℃ to 50℃ in 3.4min, realizing more efficient and rapid cooling. In addition, with the ability of rapid heating, GC-2010 Pro can significantly reduce the analysis time.
• Constant linear velocity mode quickly determines separation conditions: The constant linear velocity mode related to the separation performance is recommended for the carrier gas control and can obtain the optimum separation conditions in the shortest time compared with the previous control method by setting the column inlet pressure and flow.
• Gas saver function reduces helium consumption: Reducing running cost by gas saving is an important issue in GC operation. GC-2010 Pro reduces gas consumption by decreasing of split ratio after injection as well as automatic shutdown functions after finishing all analysis.

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GCMS-QP2050 | Single Quadrupole GC-MS

The next-generation Shimadzu GCMS-QP2050 gas chromatograph mass spectrometer, with its accumulation of impressive Shimadzu technology, will lead the way forward. New value is provided by hardware boasting astounding reliability and stability, and easy-to-operate software equipped with superior automated technology.

GCMS-QP2050 Overview

Minimum Maintenance, Maximum Progress

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LCMS-8050 | Triple Quadrupole LC-MS

Thanks to a heated ESI probe and the UFsweeper III collision cell, the Shimadzu LCMS-8050 achieves a level of sensitivity 30 times that of the LCMS-8030.The UF Technology, the ultrafast measurement technology built into the LCMS-2020 has further evolved, so measurements can now be performed even faster, without sacrificing data quality. At the same time, more compounds can now be measured in simultaneous qualitative and quantitative analysis. The system can be used in a wide range of fields for a variety of applications, such as quantitative analysis which requires high sensitivity, multicomponent simultaneous analysis, and screening.

LCMS-8050 features

• UFsensitivity^TM: High Sensitivity for Trace Quantitative Analysis
• UFswitching^TM: Polarity Switching Technology with No Compromise in Quality or Sensitivity
• UFscanning^TM: Simultaneous, Highly Reliable Quantitative and Qualitative Analysis
• UF-MRM^TM: High-Sensitivity High-Speed MRM at 555 ch/sec
• Engineered for Robustness and Easy Operation/Maintenance: Maintains High Sensitivity Even During Successive Demanding Analyses

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LCMS-8060NX | Triple Quadrupole LC-MS

The Shimadzu LCMS-8060NX is our flagship triple quadrupole LC/MS system with exceptional sensitivity and detection speeds. With our latest UFMS™ technology, this LC/MS/MS boasts increased robustness and ease-of-use, as well as an Analytical Intelligence function to streamline your analytical process and maximize your laboratory throughput.
Equipped with the new IonFocus™ electrospray unit and improved ion guides, the LCMS-8060NX delivers more reliable analysis and　maximized uptime. It also offers higher efficiency over all workflow steps, making it an ideal choice for pharmaceutical, clinical, and food/beverage companies seeking greater operational efficiency.

LCMS-8060NX features

• IonFocus™ unit: A newly-developed ESI probe with focus electrodes introduces ions into the mass spectrometer more efficiently, while expelling contaminants to reduce noise and provide more stable data. In addition, an improved heat-assist design promotes the ionization of a wide range of compounds. (Patented technology.)
• UF-Qarray™Ⅱ, UF-Lens™Ⅱ: Re-engineered ion guide improves robustness without compromising on sensitivity. Maintenance of UF-Qarray II
  and UF-Lens II can be performed easily without tools.
• Easy maintenance interface: The LCMS-8060NX inherits all the ease-of-maintenance of its predecessors. Both the desolvation line (DL), which introduces the sample into the vacuum, and the ESI capillary can be replaced easily and in a short time. The DL can be replaced while maintaining the vacuum, minimizing downtime.
• Robustness and Ease of Use: In the newly-developed IonFocus unit, the focus electrodes reduce sensitivity loss from matrix effects by expelling contaminants with greater efficiency.
• Intelligent Automation Improves Workflow Efficiency: The combination of the LCMS-8060NX and the Nexera™ series UHPLC provides a system with multiple Analytical Intelligence features, improving the efficiency of your entire workflow and maximizing analytical throughput.

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LCMS-8060 | Triple Quadrupole LC-MS

The Shimadzu LCMS-8060 features an optimized ion guide and new technologies incorporated in the ion transport optical system. As a result, the ion sampling efficiency and ion focusing capability are significantly increased, to achieve improved sensitivity, approx. 3 times better than that of the LCMS-8050. Inheriting the high-speed performance of the LCMS-8050, this flagship model in the UFMS series features both the world’s highest level of sensitivity and the world’s highest throughput. It is capable of detecting ultra trace components in complex matrices, which have been difficult to detect to date, both quickly and with high sensitivity. This will contribute to further improvements in data quality in all types of trace quantitative analysis applications, such as for biological samples, which requires the highest level of sensitivity.

LCMS-8060 features

• Sensitivity: By redefining the ion focusing capability on the UF-Qarray, the LCMS-8060 brings a meaningful impact to quantitative detection and opens new opportunities for scientists to deliver solutions that make a true difference.
• Speed: Inspired by the need to balance advanced high speed MS/MS detection technologies with unrivalled LC performance, we were the first mass spectrometry company in the world to deliver a scan speed of 15,000 u/sec and a polarity switching speed of 15 msec. In the LCMS-8060 the scan speed is now increased to 30,000 u/sec and a polarity switching speed of 5 msec making a real difference to working better and faster.
• Solutions: High-sensitivity quantitation of intact catecholamines (CAs) in human plasma.
• Stability: The robustness of the LCMS-8060 and modified ion optics was also assessed by injecting 2400 samples of femto-gram levels of alprazolam spiked into protein-precipitated human plasma extracts over a 6 day period (over 400 samples were injected each day). The RSD of peak area response was 5% over this test period, using a deuterated internal standard (alprazolam-d5) the RSD was 3.5%. As part of the robustness test the vacuum system was vented to model a transient power failure with no effect on signal response or baseline noise level.

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LCMS-9050 | Quadrupole Time-of-Flight LC-MS

The Shimadzu LCMS-9050 is a quadrupole Time-of-Flight (Q-TOF) mass spectrometer system designed with technologies developed for Shimadzu LCMS series models and that results in among the highest mass accuracy stability levels available. Shimadzu’s proprietary high precision temperature control system inhibits even tiny mass variations caused by external factors, so that the system can be used to measure accurate mass values without worrying about mass calibration. The stable positive/negative high-speed polarity switching technology enables the simultaneous analysis of positive ions/negative ions, contributing to new applications development and heightened analysis efficiency. To ensure that all users can perform analysis easily and efficiently, Shimadzu has aimed to simplify mass calibration, maintenance and other non-analysis procedures. Further, combining this system with Shimadzu’s renowned lineup of varied optional equipment enables greater utilization of the characteristics of Q-TOF while greatly expanding the range of data obtainable.

LCMS-9050 features

Simpler Accurate Mass Spectrometry

• Technologies inherited from the LCMS series
• Stable long-term mass accuracy
• Effortless tuning (Performance Assistant)
• Easy maintenance

Provides High-Speed Polarity Switching Even with TOF

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Nexera Prep | Preparative Purification Liquid Chromatograph

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Nexera XS inert | Ultra High Performance Liquid Chromatograph

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LCMS-TQ RX Series

Shimadzu‘s LCMS-TQ RX Series expands the capability and productivity of triple quadrupole mass spectrometer with performance that can be relied upon. The RX Series has been designed to generate a highly focused ion beam from the ion source to detector bringing together advanced ion guide and collision cell technologies. The result is higher data quality that makes an impact on any LC-MS/MS assay

LCMS-TQ RX Series Overview

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ICPMS-2040 Series / ICPMS-2050 Series

Shimadzu’s ICPMS-2040 and ICPMS-2050 have approximately twice the sensitivity of conventional models while simultaneously reducing argon gas consumption by roughly one third. Both models also come fully equipped with a variety of easy-to-use workflow optimization functions and software. The result is an impressive reduction in measurement times, analytical costs and environmental loads.

ICPMS-2040 / ICPMS-2050 Series Overview

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